GHK-Cu CreamGHK-Cu acetate 3% · 30 g · 30-day supply

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Four human studies

The evidence

Measured on skin, in real women.

Denser skin. Shallower wrinkles. More collagen on biopsy.

The published human work on GHK-Cu was done with creams on faces, which is exactly how you would use this one. Over twelve weeks, skin got denser and thicker, lines softened, and clarity and firmness improved.

  • Density and thickness up
  • Wrinkle depth down
  • Beat vitamin K head to head
  • Collagen confirmed by biopsy
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$99 first month, then $214.99 a month.

Three glass panels showing a copper peptide complex, a fibroblast, and bundled collagen fibers.
4 human studiesAll of them topical
179 womenAcross the three facial and eye trials
12 weeksThe length of the facial studies
Biopsy dataCollagen read from skin, not surveys

What the papers found

Four studies, in plain English.

Each card says what was applied, to how many people, for how long, and what changed. The papers are linked so you can check us.

  • 67 women aged 50 to 59
  • 12 weeks, twice daily

A GHK-Cu facial cream on the same twice-daily schedule Rebody prescribes.

Laxity, clarity, firmness, and appearance improved. Fine lines, coarse wrinkles, and mottled pigmentation all came down. Density and thickness rose, and skin biopsies showed the cream stimulated new cell growth in the dermis.

Pickart, Vasquez-Soltero & Margolina, BioMed Res Int, 2015

What improved

The four things they measured.

These are the outcomes the researchers scored, not adjectives from a brand deck.

01

Density and thickness

Both went up in every facial and eye study in the review. Thicker dermis is the structural reason skin stops looking thin and slack.

02

Fine lines and wrinkle depth

Lines softened and wrinkles measured shallower over twelve weeks. The 67-woman study also recorded fewer coarse wrinkles.

03

Laxity, clarity, and firmness

The three measures that decide whether a face reads tired or rested. All three improved on GHK-Cu cream.

04

Mottled pigmentation

Uneven patches came down in the twice-daily facial study, which is the schedule Rebody prescribes.

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Route matters

The studies used the route you would.

Plenty of peptides are sold on evidence collected some other way, through a needle or a pill, and then applied to a product you rub on your face. GHK-Cu is the opposite case. The human cosmetic work is topical, twelve weeks long, and in one study on the same twice-daily schedule this cream is prescribed for.

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A glass cross-section of skin layers with a copper peptide complex above the surface and fibroblasts and collagen fibers below.

Why it works at all

A repair signal you stop making.

GHK-Cu is native to your body. The interesting part is what happens to it, and to your skin, as the supply falls away.

A diagram in glass and copper: a copper filament labelled plasma GHK-Cu thins as it runs to the right, passes through a panel of repair pathways, and reaches a fibroblast that is laying down woven collagen fibers.
01GHK-Cu falls with age

Plasma GHK drops steeply from your twenties onward. The peptide your skin repairs with becomes scarce exactly when you start needing it.

02It signals the repair genes

Gene-expression work published in 2018 found GHK-Cu shifts a broad set of pathways toward tissue repair and matrix building.

03Fibroblasts build again

Cell and tissue studies measured higher collagen and elastin output. That is the scaffold under everything you see in the mirror.

Rebody customers

What twelve weeks looked like for them.

01
After ten weeks with the GHK-Cu cream, my skin is not as dry, and makeup goes on much smoother than it did ten weeks ago. I asked Rebody about using the cream with retinol and got a clear answer the same day.
Makeup sits better nowVerified Rebody customer · About 10 weeks
02
I ordered the GHK-Cu cream for my face, but the biggest change has been my neck. It looks less dry and makeup does not settle into the same lines.
My neck looks betterVerified Rebody customer · 12 weeks
03
I have bought more expensive creams than I want to admit and usually stop using them after a few weeks. The GHK-Cu cream is the first one I have used consistently. My skin feels smoother, the dry areas are gone and makeup sits much better around my mouth and neck.
The first skincare product I have stuck withVerified Rebody customer · About 3 months
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Evidence-matched routeThe Rebody GHK-Cu 3% topical cream in a frosted 30 gram airless pump beside a blue cream swatch.

Your treatment

The topical route, at 3%

A 30 g airless pump of GHK-Cu acetate 3%, used morning and evening for a full 30 days.

First month$99

Then$214.99/mo

Per day, month one$3.30

Active
GHK-Cu acetate
Strength
3%
Route
Topical cream
Package
30 g airless pump
Supply
30 days
Directions
Twice daily, morning and evening
Storage
Keep refrigerated
Status
Prescription only
  • GHK-Cu acetate 3% cream, 30 g
  • A full month of twice-daily use
  • Private online visit, no appointment
  • Licensed U.S. provider review
  • Filled by a licensed U.S. compounding pharmacy
  • Printed directions, storage, and beyond-use date
Get GHK-Cu cream for $99

$99 today, a saving of $115.99. Then $214.99 a month.

Research questions

What the studies did and did not cover.

How many people were in the human studies?

Four published human studies are summarised in the 2015 review: 71 women over twelve weeks, 67 women aged 50 to 59 over twelve weeks of twice-daily use, 41 women over twelve weeks in an eye-cream comparison, and a thigh study in women around age 50 that read collagen from skin biopsies.

Were they done with creams or injections?

Creams, applied to the skin. That matters, because a topical route is what Rebody prescribes. The evidence and the product line up.

Did anything beat a comparison treatment?

Yes. In the eye-cream study GHK-Cu did better than both a placebo and a vitamin K cream. In the biopsy study, collagen rose in 70% of the GHK-Cu group, against 50% on vitamin C and 40% on retinoic acid.

Did they test this exact cream?

No. The published studies used cosmetic GHK-Cu creams, and the review does not print the percentage each one carried. Rebody's formula is a compounded prescription cream at GHK-Cu acetate 3%.

How long before the studies saw a change?

The facial and eye studies ran twelve weeks. The biopsy study ran one month. Plan a full twelve-week course before you decide.

Where can I read the research myself?

Both papers are open access on PubMed Central and linked under the study cards on this page. Read them rather than taking a marketing summary on trust.

Important safety information

Read this before you start.

GHK-Cu acetate 3% cream is a compounded prescription medicine applied to the skin. Compounded medicines are not FDA-approved. A licensed provider decides whether it is appropriate for you.

Tell your provider about every medicine, prescription cream, supplement, and skin treatment you use, about copper allergy or Wilson disease, and about pregnancy or breastfeeding.

Stop and contact your provider if you get redness, burning, itching, swelling, or a rash where you applied the cream. Get urgent help for hives, facial swelling, or trouble breathing.

Do not use it on broken skin or in the eyes. Keep it refrigerated and follow the directions, storage, and beyond-use date printed on your label.

Important safety information · GHK-Cu acetate 3% topical cream
A close crop of facial skin with a mineral-blue streak of GHK-Cu cream across the cheek.

Topical route, topical evidence

Put the research on your face.

Twelve weeks is the course the research used. $99 starts yours.

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$99first month, then $214.99

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