Enclomiphene
- One tablet each morning
- Estrogen receptors in the brain are blocked
- The pituitary keeps sending LH and FSH
- Your testes make the testosterone
The loop that made your testosterone is the loop that keeps making it.
Enclomiphene TabletsRaise it, don't replace it
$166.33/mofor the first 3 months
Start my visitNo needlesOne tablet each morning
Your own signalLH and FSH stay in play
Labs read firstLH, FSH, total T, SHBG
Raise your testosterone. Keep the factory.
Testosterone replacement hands you the hormone and switches off the system that makes it. Enclomiphene turns that system up instead. One tablet each morning, and the production stays yours.
- Works through your own LH and FSH signal
- Sperm concentration held in a randomized trial
- No injections, no gels, no pellets
$166.33/mo for your first 3 months
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Back in the gym.
Verified enclomiphene customer
First 3 months$166.33/mo
Start my visit The part nobody tells you first
Replacement buys the hormone and sells the factory.
Your testes make testosterone because the pituitary keeps sending LH and FSH. Put testosterone in from outside and the brain reads the level as handled, so it stops sending. The testes go quiet. Sperm production falls. Testicular volume drops. That is not a badly run protocol. That is how replacement works.
Enclomiphene starts one step earlier. It blocks the estrogen receptors that carry the shut-down message, so the pituitary keeps sending LH and FSH and your testes keep doing the job. The testosterone in your blood is still testosterone you made.
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LH and FSH are the messages. Enclomiphene keeps them moving.
Two routes to the same number
Follow the signal, or skip it.
Testosterone replacement
- Injection, gel, or pellet on a schedule
- Testosterone arrives from outside
- The brain reads the level and stops signalling
- Your testes stand down
The number comes up. The system that produced it goes offline.
Nine rows, one decision.
Both routes raise testosterone. Everything else about them is different, and most of the differences show up after month one.
| Decision | Enclomiphene | Testosterone replacement |
|---|---|---|
| How the number goes up | Your own testes make more of it | The dose is the testosterone |
| LH and FSH | Keep signalling | Go quiet while you are on it |
| Your own production | Stays running | Stands down and stays down |
| Sperm concentration | Maintained in a randomized Phase II trial | Falls; suppression is the expected effect |
| Routine | One oral tablet, every morning | Injections, gels, or pellets on a set schedule |
| Travel | A bottle in a bag | Needles, vials, cold chain, or a gel window |
| Monitoring | LH, FSH, total testosterone, SHBG, estradiol, symptoms | Testosterone, hematocrit, estradiol, PSA where appropriate |
| Stopping | Nothing was replaced, so nothing has to restart | The suppressed axis has to come back on its own |
| What it costs here | $498.98 for 90 days, then $599.97 every 3 months | Varies by form and clinic. Rebody does not prescribe it |
Rebody prescribes enclomiphene. It does not prescribe testosterone replacement, so the right column describes the category rather than a Rebody product. Sperm and testosterone findings come from Wiehle 2014 and Kaminetsky 2013, cited in full below.
Start my online visitWhat replacement costs you
Two things replacement does that a tablet does not.
Both routes raise the number. Only one of them asks your body and your household to carry these.
01 · Testicular volume
Exogenous testosterone shrinks testicular volume over time.
Put testosterone in from outside and the pituitary stops sending LH and FSH. The testes have nothing to answer, so they stand down, and the tissue that used to do the work gets smaller the longer you stay on it. That is not a badly run protocol. It is what replacement does.
On enclomiphene the signal keeps arriving, so the testes stay in the loop and keep working.
02 · Household exposure
Testosterone gels carry a skin-transfer warning for partners and children.
A gel sits on your skin, and skin touches other people. That is why the warning names partners and children specifically, and why a gel routine comes with rules about covering the site, washing your hands, and who can hug you and when.
A tablet you swallow transfers to nobody. There is no application site and no window to manage.
Fertility
If children are still on the table, this is the whole call.
The randomized Phase II trial measured it directly. Sperm concentration was maintained on enclomiphene citrate and suppressed on topical testosterone gel. Kaminetsky 2013 found the same direction: oral enclomiphene citrate stimulated endogenous testosterone production and sperm counts in men with low testosterone.
- Say the fertility part out loud in your visit, even if the answer is “maybe someday”.
- Individual outcomes differ, and your provider reads your own numbers before deciding.
The exit
What happens the day you stop.
Every man asks this second and it changes the answer to the first question.
Stopping enclomiphene
Your own production was never handed off, so there is nothing to hand back. Testosterone settles toward the level you make without treatment. Time the follow-up labs with your provider so you can see where you actually land.
Stopping replacement
The pituitary spent the whole course being told to stand down. After the last dose it has to start signalling again, and recovery takes time. Some men need a supervised restart to get the loop running.
The fair version
When replacement is still the right answer.
Enclomiphene raises LH and FSH, so it needs testes that still answer them. When the loop cannot respond, a tablet has nothing to push on and replacement is the honest route. That is not a judgement call made from a symptom list. It is what 4 numbers say.
- LH
- FSH
- Total testosterone
- SHBG
A licensed provider reads them before writing anything. If enclomiphene is the wrong route for you, you hear that instead of a prescription.
Start my online visitVerified customer reviews
Men who wanted the number up and the loop intact.
Back in the gym
“I am about three months into the enclomiphene program. My afternoons are better, I am back in the gym and my sex drive has improved. My Rebody doctor has been easy to reach and explained when I needed to do my next labs.”
My wife noticed first
“I was not sure the enclomiphene was doing much until my wife pointed out that I had stopped falling asleep on the couch after dinner and seemed more engaged. I have started lifting again too. Rebody sends the lab reminders before I think to look for them, and my last refill question was answered that afternoon.”
I feel like myself again
“Before enclomiphene, I spent a long time feeling tired, unmotivated and not like myself, and kept blaming age and work. My doctor listened, explained my labs clearly and gave me a plan that has made a huge difference. I am training again, have energy for my family after work and my confidence is back. The care team has also been there every time I have needed them.”
Enclomiphene against TRT
The questions that decide the route.
Strength, fertility, switching, stopping, supplies, and the one case where replacement wins.
Is enclomiphene as strong as TRT?
They work differently, so the comparison is not a straight contest. In a randomized Phase II trial, enclomiphene citrate raised total testosterone into the normal range in men with low testosterone. TRT sets the level directly, which is why it can be pushed higher, and that is also why it switches your own production off. Your labs and your goals decide which trade is the right one.
Will enclomiphene protect my fertility?
In the randomized Phase II trial, sperm concentration was maintained on enclomiphene and suppressed on topical testosterone gel. Kaminetsky 2013 reported that oral enclomiphene citrate stimulated endogenous testosterone production and sperm counts in men with low testosterone. Fertility outcomes still depend on the individual, so tell your provider if children are part of the plan.
Can I switch from TRT to enclomiphene?
Tell your provider exactly what you are on, at what dose, and for how long. Coming off replacement is its own decision, and the labs a provider reads first are LH, FSH, total testosterone, and SHBG, because those say whether your own signal has come back yet.
What happens to my testosterone if I stop enclomiphene?
Nothing was replaced, so nothing has to be restarted. The signal your body was already using is the signal that carries on, and testosterone settles back toward the level you produce without treatment. Talk to your provider before you stop so the follow-up labs are timed properly.
Does enclomiphene need injections or supplies?
No. It is an oral flex-dose tablet at 12.5 mg or 25 mg. Each shipment holds 90 tablets, a 90-day supply, taken as one tablet each morning. There are no needles, no gels, no application windows, and no cold chain.
When is TRT still the better answer?
When the testes cannot respond to the signal. Enclomiphene works by raising LH and FSH, so it needs a loop that still answers them. That is exactly what LH, FSH, total testosterone, and SHBG tell a provider before anything is prescribed. If the loop cannot respond, a provider will say so rather than sell you a tablet that has nothing to work with.
Safety and prescribing
Important safety information.
Enclomiphene is a prescription medication for men. Tell your provider about all medications and supplements, allergies, prostate or cardiovascular history, fertility plans, and your complete health history. Reported side effects include headache, nausea, hot flashes, mood changes, and joint discomfort.
Stop treatment and seek urgent care for chest pain, shortness of breath, vision changes, or signs of a serious allergic reaction such as trouble breathing or facial swelling. Do not share this medication. It is not for use by women or by anyone who is pregnant or may become pregnant.
- Wiehle RD, et al. Enclomiphene citrate stimulates testosterone production while preventing oligozoospermia: a randomized phase II clinical trial. Fertility and Sterility. 2014.
- Kaminetsky J, et al. Oral enclomiphene citrate stimulates the endogenous production of testosterone and sperm counts in men with low testosterone. Journal of Sexual Medicine. 2013.
Ready to start?
Share your symptoms, your history, and any recent bloodwork. A licensed provider reads your labs and tells you which route your numbers support.
Start my online visitDone with TRT?
The next question is how hard to push. See 12.5 mg and 25 mg side by side, and what changes between them.
Compare 12.5 mg and 25 mgEnclomiphene tablets at home
Higher testosterone, still yours.
$166.33/monthfor your first 3 monthsStart my online visit
90 tablets, one every morning, a 90-day supply. Provider review and free shipping included.